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| Brand | Incepta Pharmaceuticals Ltd. |
|---|---|
| Product Name | Amphoject |
| Variant/Specs | 50mg/vial (IV Infusion) |
| Packaging/Type | Premium Retail Packaging |
| Reconstitution Process | Medical personnel must aseptically add 12 mL of Sterile Water for Injection to the vial to create a 4 mg per mL concentration, followed by vigorous shaking for 30 seconds to disperse the powder. |
|---|---|
| Visual Inspection | Before administration, the reconstituted yellow translucent suspension must be visually inspected for any particulate matter, and shaking should continue until the drug is completely dispersed. |
| Storage Conditions | Unopened vials of the lyophilized material must be stored in a controlled environment at temperatures up to 25 degrees Celsius to ensure the long-term stability of the active chemical components. |
| Post-Reconstitution Stability | After the initial preparation, the reconstituted product concentrate can be stored for a maximum of 24 hours, provided it is kept in a refrigerated environment between 2 to 8 degrees Celsius. |
| Dosage Guidelines | Initial treatment typically involves a test dose of 1 mg infused over 20 to 30 minutes, with maintenance doses adjusted between 0.25 to 1 mg per kg daily based on the patient's clinical response. |
| Generic Name | This product contains Amphotericin B as a lyophilized powder for intravenous infusion, specifically formulated for the treatment of severe and life-threatening systemic fungal infections in clinical settings. |
|---|---|
| Strength and Potency | Each individual vial is manufactured to contain exactly 50 mg of the active ingredient, ensuring consistent dosing for patients requiring intensive antifungal therapy as prescribed by doctors. |
| Manufacturer Details | This medicine is produced by Incepta Pharmaceuticals Ltd., a leading pharmaceutical company in Bangladesh that adheres to strict international quality control standards for all its injectable products. |
| Therapeutic Classification | It belongs to the class of other antifungal preparations and is primarily used as a systemic treatment for patients who are unresponsive to conventional deoxycholate formulations. |
| Pharmacological Action | The drug works by binding irreversibly to ergosterol in the fungal cell membrane, which creates transmembrane channels that lead to cytoplasmic leakage and the eventual death of the fungus. |
| Contraindication Info | This medication is strictly contraindicated for individuals with a known hypersensitivity to amphotericin B or its constituents, unless a physician determines the benefits outweigh the clinical risks. |
|---|---|
| Potential Side Effects | Common adverse reactions include fever, chills, nausea, vomiting, and potential disturbances in renal function, necessitating close medical observation during the entire infusion and dosing period. |
| Pregnancy Category | It is listed as Pregnancy Category B, indicating that while there are no controlled studies in pregnant women, it should only be used under expert medical guidance when absolutely necessary for health. |
| Drug Interactions | The risk of renal toxicity is enhanced when this drug is used alongside other nephrotoxic medications, and it may also show increased toxicity when combined with flucytosine during treatment. |
| Medical Supervision | Administration must be performed only by medically trained personnel who are equipped to monitor the patient for any signs of hypotension, cardiac arrhythmias, or other severe systemic reactions. |
Finding a reliable source for critical antifungal medications like Amphoject 50 mg in Bangladesh requires absolute trust in authenticity and handling. This potent Amphotericin B formulation by Incepta Pharmaceuticals is specifically designed to combat life-threatening systemic fungal infections and visceral leishmaniasis with medical precision. Pentamart ensures that these vital vials are managed through a secure supply chain, backed by our Doctor-CEO guarantee for your peace of mind. By prioritizing genuine pharmaceutical standards, we help you focus on the recovery of your loved ones while we handle the logistics of safety and reliability.
Key Features:
Targeted Antifungal Action: This medication binds to ergosterol in the fungal cell membrane, creating channels that cause leakage of intracellular components. This mechanism ensures the treatment effectively disrupts the integrity of fungi.
Broad Spectrum Indications: It is clinically indicated for empirical therapy in febrile, neutropenic patients and for treating serious infections caused by Aspergillus or Candida species. This versatility makes it a cornerstone for complex fungal conditions.
Cryptococcal Meningitis Support: The formulation is authorized for the treatment of Cryptococcal Meningitis in patients living with HIV, providing a critical medical intervention. It addresses the needs of patients where other treatments may be refractory.
Visceral Leishmaniasis Treatment: This IV infusion serves as a vital therapeutic option for visceral leishmaniasis, helping to clear parasites from the body during treatment. It offers a necessary medical path for patients suffering from this severe disease.
Reduced Toxicity Profile: Compared to standard deoxycholate, this preparation is formulated to be significantly less toxic, offering a safer alternative for renal patients. This allows medical personnel to manage severe infections while minimizing risks.
The Pentamart Trust Guarantee: At Pentamart, we understand how critical genuine products are in Bangladesh. Built on our "Fortress of Trust" and backed by our Doctor-CEO quality control guarantee, every product is guaranteed 100% original, fresh, and ethically sourced. When you shop with Pentamart, you get pure, uncompromised quality delivered straight to your door.
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